重组人白介素-1受体拮抗剂蛋白
| 英文名称 | Recombinant human IL-1Ra protein, His |
| 中文名称 | 重组人白介素-1受体拮抗剂蛋白 |
| 别 名 | Recombinant Human Interleukin-1 receptor antagonist His Tag; Recombinant human IL-1Ra protein, His |
| 理论分子量 | 17kDa |
| 检测分子量 | 20 kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | ＞0.5 mg/ml |
| 物 种 | Human |
| 序 列 | 26-177/177 |
| 纯 度 | >95% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not analyzed |
| 表达系统 | E.coli |
| 活性 | Not tested |
| 标签 | His |
| 缓 冲 液 | PBS (pH=7.4) |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | IL-1RA is a member of the interleukin 1 cytokine family. IL1Ra is secreted by various types of cells including immune cells, epithelial cells, and adipocytes, and is a natural inhibitor of the pro-inflammatory effect of IL1β. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. L-lra-重组人白介素-1受体拮抗剂，通过与白细胞介素-1的Ⅰ型和Ⅱ型受体结合，特异性地阻断白细胞介素-1的生物学作用。白介素1受体拮抗剂(IL-1Ra)是体内天然的一种对IL-1有拮抗作用的细胞因子。国际上对其的研究愈来愈受到重视。 重组人白介素1受体拮抗剂(rhIL-1Ra)作为一种生物制剂已经FDA批准应用于临床治疗细胞因子。 重组白介素1受体拮抗剂，分子量约17kD，纯度大于98%。 |
| 产品图片 |
 The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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