FITC标记的补体C7抗体
产品名称： FITC标记的补体C7抗体
英文名称： Anti-C7 /FITC
产品编号： HZ-15256R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-C7 /FITC Conjugated antibody
FITC标记的补体C7抗体
| 英文名称 | Anti-C7 /FITC |
| 中文名称 | FITC标记的补体C7抗体 |
| 别 名 | C7; CO7_HUMAN; complement component 7; Complement component C7. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 91kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human C7 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. [provided by RefSeq, Jul 2008] Function: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Subunit: Monomer or dimer; as a C5b-7 complex it can also form multimeric rosettes. MAC assembly is initiated by protelytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and multiple copies of the pore-forming subunit C9. Subcellular Location: Secreted. Post-translational modifications: C7 has 28 disulfide bridges. O- and C-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. DISEASE: Defects in C7 are a cause of complement component 7 deficiency (C7D) [MIM:610102]. A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Similarity: Belongs to the complement C6/C7/C8/C9 family. Contains 1 EGF-like domain. Contains 1 LDL-receptor class A domain. Contains 1 MACPF domain. Contains 2 Sushi (CCP/SCR) domains. Contains 2 TSP type-1 domains. Database links: Entrez Gene: 730 Human Entrez Gene: 109828 Mouse Entrez Gene: 117517 Rat Omim: 217070 Human SwissProt: P10643 Human Unigene: 78065 Human Unigene: 208034 Mouse Unigene: 232711 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
补体C7是补体系统的一个组成部分。它参与了膜攻击复合物（MAC）的形成。C7缺乏者易发生细菌感染。[ RefSeq，JUL 2008 ]