Product: Anti-ABCA1, clone AB1.G6
Cat. No.: MC-388 (100 μg)
Specificity:
Mutations in the ABCA1 gene (ATP-binding
cassette transporter 1) are associated with
Tangier disease (TD). TD is an autosomal
recessive disorder resulting from an absence of
plasma HDL, cholesterol ester depositing in the
reticulo-endothelial system and disorders in
cellular lipid trafficking. It is expressed on the
plasma membrane and the Golgi complex and is
regulated by cholesterol flux. Regulation of the
cholesterol flux between HDL and macrophages
is competitive between ABCA1 and SR-BI.
Species Specificity:
Human. Other species not tested.
Immunogen:
Peptide corresponding to amino acids 1800-
2260.
Ig Isotype:
Mouse IgG1
Format:
100 μg of antibody at 1 mg/mL in PBS, pH 7.4,
with 0.5% sodium azide.
Storage and Stability:
Store at -20°C. Aliquot to avoid repeated
freeze/thaw cycles.
Applications and Suggested Dilutions:

Immunohistochemistry

Western blot

ELISA

Immunoprecipitation
The optimal dilution for a specific application
should be determined by the researcher.
Limitations:
For in vitro research use only. Not for use in
diagnostics or in humans.
Warranty:
No warranties, expressed or implied, are made
regarding the use of this product. KAMIYA
BIOMEDICAL COMPANY is not liable for any
damage, personal injury, or economic loss
caused by this product