FITC标记的低密度脂蛋白受体结构域蛋白1抗体
产品名称： FITC标记的低密度脂蛋白受体结构域蛋白1抗体
英文名称： Anti-LDLRAD1/FITC
产品编号： HZ-18207R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-LDLRAD1/FITC Conjugated antibody
FITC标记的低密度脂蛋白受体结构域蛋白1抗体
| 英文名称 | Anti-LDLRAD1/FITC |
| 中文名称 | FITC标记的低密度脂蛋白受体结构域蛋白1抗体 |
| 别 名 | Low density lipoprotein receptor A domain containing 1; Low density lipoprotein receptor class A domain containing 1; low density lipoprotein receptor class A domain containing protein 1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 22kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LDLRAD1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: LDLRAD1 is a 205 amino acid protein that belongs to the LDLR family and contains three LDL-receptor class A domains. Existing as three alternatively spliced isoforms, LCLRAD1 is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. Function: LDLRAD1 is a member of the LDLR family of receptors and has three named isoforms. Subcellular Location: Cell Membrane; Single pass membrane protein Database links: Entrez Gene: 388633 Human SwissProt: Q5T700 Human Unigene: 439583 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
LDLRAD1是属于LDLR家族的205个氨基酸，含有三个LDL受体A类结构域。LCLRAD1作为三种可选择的剪接异构体存在，由位于人类染色体1上的基因编码，该基因跨越2.6亿个碱基对，包含3000多个基因，占人类基因组的近8％。染色体1包含许多疾病相关基因，包括那些与家族性腺瘤性息肉病、Stickler综合征、帕金森病、Gaucher病、精神分裂症和Usher综合征相关的基因。染色体1异常存在于各种癌症中，包括头颈癌、恶性黑色素瘤和多发性骨髓瘤。